drugset / Trial / NCT06153602
Effectiveness of Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in TURP Surgery
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The goal of this clinical trial is to compare pain after surgery in patients undergoing Transurethral Resection of Prostate. The main question it aims to answer are: Intrathecal nalbuphine as an adjuvant to local anesthetic will better provide pain relief after TURP surgery. Participants will be given a combination of nalbuphine and local anesthetic when getting a spinal block. Researchers will compare control group, given look-alike solution that contains no active drug to see if nalbuphine will better provide pain relief after surgery.
Timeline
- Start
- 2023-12-07
- Primary completion
- 2024-11-27
- Completion
- 2024-11-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nalbuphine | Small molecule | 0.8 mg | Intrathecal |
| Subject | Nalbuphine | Small molecule | 4 mg | Intrathecal |
| Background | Acetaminophen | Small molecule | 500 mg | Oral |
| Background | Bupivacaine | Other / unclassified | 0.5 % | Intrathecal |
| Background | Ondansetron | Other / unclassified | 8 mg | Intravenous |
Indications
No indication recorded.