Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia

Phase 4 Unknown 168 enrolled Tribhuvan University Teaching Hospital, Institute Of Medicine.

RandomizedSequentialDouble-blindTreatment

Summary

In patients undergoing elective LSCS under subarachnoid block, group BF will receive 0.5% hyperbaric bupivacaine 10mg (2ml) with fentanyl 10 mcg (0.2ml) with total of 2.2 ml and group BD will receive 0.5% hyperbaric bupivacaine 10 mg with Dexmedetomidine 5mcg (0.2ml) total volume 2.2ml. Assessment of intraoperative visceral pain will be done by self-reporting of patients, who are previously educated, as poorly localized discomfort or dragging, pulling heaviness or unpleasant feeling or pain with or without nausea and will be categorized according to preformed scale

Timeline

Start: 2024-04
Primary completion: 2024-08
Completion: 2024-09

Publications

Dhakal S, Shrestha M, Gautam E, Suwal A, Dhakal S, Dhakal S. Comparison of hyperbaric bupivacaine with fentanyl vs. hyperbaric bupivacaine with dexmedetomidine in reducing visceral pain during cesarean delivery under spinal anesthesia: study protocol. Pain Manag. 2025 Oct;15(10):651-658. doi: 10.1080/17581869.2025.2543232. Epub 2025 Aug 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	5 ug	Intrathecal
Comparator	Fentanyl	Other / unclassified	10 ug	Intrathecal
Comparator	Bupivacaine	Other / unclassified	10 mg	Intrathecal

Indications

No indication recorded.