drugset / Trial / NCT06557018
Efficacy and Safety of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The goal of this clinical trial is to learn if drug Bupivacaine liposomes works better than traditional peri-articular injection for Control of Pain in Total Knee Arthroplasty. It will also learn about the safety of drug Bupivacaine liposomes. The main questions it aims to answer are: Does Bupivacaine liposomes works better than traditional peri-articular injection for Control of Pain in Total Knee Arthroplasty. Researchers will compare Bupivacaine liposomes to traditional peri-articular injection to see if drug Bupivacaine liposomes works better for Control of Pain in Total Knee Arthroplasty Participants will: Receive peri-articular injection in total Knee Arthroplasty. checkups and tests During hospitalization.
Timeline
- Start
- 2024-06-25
- Primary completion
- 2024-08-31
- Completion
- 2024-09-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 266 mg | Other |
| Comparator | Epinephrine | Other / unclassified | 0.4 mg | Other |
| Comparator | Morphine | Other / unclassified | 5 mg | Other |
| Comparator | Ropivacaine | Other / unclassified | 400 mg | Other |