drugset / Trial / NCT06641206
Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain
RandomizedParallel-groupDouble-blindTreatment
Summary
Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to anesthesia and local anesthetics. Given its potential for pain management, exploring DEX as a treatment for KOA could offer a new and promising approach.
Timeline
- Start
- 2024-09-17
- Primary completion
- 2025-01
- Completion
- 2025-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 20 mg | Other |
| Comparator | Dexmedetomidine | Other / unclassified | 3 ug/kg | Other |
| Comparator | Triamcinolone Acetonide | Other / unclassified | 1 ml | Other |