drugset
drugset / Trial / NCT06772779

A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026)

NCT06772779 ↗

Phase 1 Completed 36 enrolled Merck Sharp & Dohme LLC
RandomizedCrossoverOpen-labelBasic science

Summary

The main goal of this study is to learn what happens in a person's body over time when they take enlicitide decanoate with warfarin or lisinopril. Researchers want to learn if the amount of warfarin in a person's blood is similar when warfarin is taken alone or with enlicitide decanoate. Enlicitide decanoate is a new medicine that lowers the amount of cholesterol in a person's blood. Warfarin is a drug that reduces risk of blood clotting, and lisinopril is a drug that lowers blood pressure.

Timeline

Start
2024-04-01
Primary completion
2024-06-04
Completion
2024-06-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Enlicitide Decanoate Unknown — Oral
Subject LISINOPRIL ANHYDROUS Small molecule — Oral
Subject Warfarin Small molecule — Oral

Indications

No indication recorded.