drugset / Trial / NCT06775275

A Study of Adebrelimab in Combination with Chemo with or Without Bevacizumab Neoadjuvant Therapy for Resectable NSCLC

NCT06775275

RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, multicenter, randomized, uncontrolled Phase II study to assess the efficacy and safety of adebrelimab in combination with chemotherapy with or without bevacizumab for the treatment of resectable Stage II-IIIB (T3N2) NSQ-NSCLC and to explore biomarkers associated with efficacy.

Timeline

Start
2024-09-24
Primary completion
2025-12-31
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Adebrelimab Monoclonal antibody
Subject Bevacizumab Monoclonal antibody
Background Carboplatin Small molecule
Background Cisplatin Other / unclassified
Background Docetaxel Small molecule
Background Nedaplatin Small molecule
Background Paclitaxel Small molecule
Background Pemetrexed Small molecule