drugset / Trial / NCT06789575

Comparison of Bupivacaine Wound Infiltration Versus Wound Instillation to Minimize Postoperative Pain After Thyroid Surgery

NCT06789575

Phase 3 Not yet recruiting 102 enrolled Assiut University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Pain management following thyroidectomies, which can cause mild to moderate postoperative pain, particularly in the first 24 hours following surgery, has received little attention . The incision of the wound, neck hyperextension, retraction of the wound margins during surgery, and dissection are the main reasons of post-thyroidectomy discomfort . After thyroid surgery, pain management improves patients' quality of life and facilitates a speedy return to regular daily activities. the aim of the study to evaluate the effects of bupivacaine instillation after thyroidectomy against infiltration into the surgical field in order to reduce postoperative discomfort following thyroid surgery.

Timeline

Start
2025-03-01
Primary completion
2026-03-01
Completion
2027-05-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 0.25 % Other
Comparator Bupivacaine Other / unclassified 10 ml Other
Comparator Epinephrine Other / unclassified 15 ug Other
Comparator Lidocaine Other / unclassified 70 ml Other

Indications

No indication recorded.