drugset / Trial / NCT06861244
Embryonal Tumor With Multilayered Rosettes
Phase 2
Recruiting
70 enrolled
University of California, San Francisco
Pediatric Neuro-Oncology Consortium · collabSolving Kids' Cancer · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is an open-label, comprehensive, iterative investigation of evaluating the use of induction chemotherapy, high-dose chemotherapy, and focal radiation therapy in children with newly diagnosed Embryonal Tumor With Multilayered Rosettes (ETMR).
Timeline
- Start
- 2025-03-06
- Primary completion
- 2030-09-30
- Completion
- 2032-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Carboplatin | Small molecule | — | — |
| Background | Cisplatin | Other / unclassified | — | — |
| Background | Cyclophosphamide | Other / unclassified | — | — |
| Background | Cytarabine | Small molecule | — | — |
| Background | Dactinomycin | Unknown | — | — |
| Background | Doxorubicin | Other / unclassified | — | — |
| Background | Temozolomide | Small molecule | — | — |
| Background | Thiotepa | Other / unclassified | — | — |
| Background | Topotecan | Small molecule | — | — |
| Background | Vincristine | Small molecule | — | — |
| Background | filgrastim | Protein / enzyme biologic | — | — |