drugset / Trial / NCT06907277

Dexmedetomidine Enhancing the Recovery After Cardiac Surgery

NCT06907277 ↗

Completed 75 enrolled Benha University
RandomizedParallel-groupSingle-blindTreatment

Summary

Enhanced Recovery After Surgery (ERAS) aims to facilitate a quicker and smoother recovery period following surgical procedures. The implementation of these protocols may lead to patients returning to their daily activities sooner, experiencing greater satisfaction with their care, and potentially encountering fewer complications, ultimately contributing to shorter hospital stays. However, a common challenge in the postoperative phase is postoperative delirium(POD). This complication can lead to both immediate and long-term cognitive impairments, negatively impact overall health outcomes, and increase the financial burden on the healthcare system. Interestingly, dexmedetomidine, known as DXM, is a medication that selectively targets certain receptors in the brain and offers sedative properties with minimal impact on breathing. This characteristic is noteworthy because it may help regulate sleep patterns and support the preservation of cognitive function during the recovery period.

Timeline

Start
2024-08-30
Primary completion
2024-12-01
Completion
2025-01-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.15 ug/kg —
Comparator Fentanyl Other / unclassified 0.3 ug/kg —
Comparator Lidocaine Other / unclassified 1.5 mg/kg —

Indications

No indication recorded.