drugset / Trial / NCT06918015

Zanubrutinib Plus GCVP (Obinutuzumab, Cyclophosphamide, Vindesine, Prednisolone) in Previously Untreated Follicular Lymphoma

NCT06918015

Phase 2 Not yet recruiting 58 enrolled Zhejiang Cancer Hospital
NaSingle-groupOpen-labelTreatment

Summary

Previously untreated patients with follicular lymphoma are treated with the ZGCVP regimen (zanubrutinib, obinutuzumab, cyclophosphamide, vindesine, prednisolone) for 6 cycles.

Timeline

Start
2025-05-01
Primary completion
2028-05-01
Completion
2030-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Zanubrutinib Small molecule 160 mg Oral
Background Cyclophosphamide Other / unclassified 750 unknown Intravenous
Background Obinutuzumab Monoclonal antibody 1000 mg Intravenous
Background Prednisolone Other / unclassified 30 mg Oral
Background Vindesine Small molecule 3 mg/m2 Intravenous

Indications