drugset / Trial / NCT07158476
Efficacy of Methylprednisolone for Pain Control After ACL Repair
RandomizedParallel-groupOpen-labelSupportive care
Summary
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.
Timeline
- Start
- 2025-10-21
- Primary completion
- 2030-09
- Completion
- 2031-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketorolac | Other / unclassified | 10 mg | Oral |
| Comparator | Meloxicam | Small molecule | 15 mg | Oral |
| Comparator | Methylprednisolone | Other / unclassified | 4 mg | Oral |
| Comparator | Acetaminophen | Small molecule | 325 mg | Oral |
| Comparator | Gabapentin | Small molecule | 300 mg | Oral |
| Comparator | Hydrocodone | Unknown | 5 mg | Oral |
Indications
No indication recorded.