drugset / Trial / NCT07203287

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

NCT07203287

Phase 4 Recruiting 490 enrolled The University of Texas Medical Branch, Galveston
RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is "The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."

Timeline

Start
2025-08-26
Primary completion
2026-12-31
Completion
2027-08-26

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cisatracurium Small molecule
Comparator Neostigmine Other / unclassified
Comparator Rocuronium Other / unclassified
Comparator Sugammadex Other / unclassified

Indications

No indication recorded.