drugset / Trial / NCT07339527

EZH2 Inhibitor Zeprumetostat in Combination Therapy for Patients With Relapsed or Refractory Mature T-cell and NK-cell Lymphomas

NCT07339527

Phase 1/2 Not yet recruiting 60 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, multicenter, open-label, phase Ib/II clinical study to evaluate the safety and efficacy of EZH2 inhibitor Zeprumetostat in combination therapy for patients with relapsed or refractory mature T-cell and NK-cell lymphomas.

Timeline

Start
2026-01-01
Primary completion
2028-01-01
Completion
2030-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Golidocitinib Small molecule 150 mg Oral
Subject Tucidinostat Small molecule 20 mg Oral
Subject Zeprumetostat Small molecule 350 mg Oral