The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus
Summary
"Assessment of postoperative pain with conventional and tumescent local anesthesia in the laser treatment of pilonidal sinus." The aim of this study is to: examine the possible difference in postoperative pain between two local anesthesia procedures after laser treatment of pilonidal sinus disease on the first and second postoperative day, as well as one week after surgery. During the procedure, two well-established anesthesia techniques are used to make the surgical area painless. The first is local anesthesia, in which the anesthetic is injected into and under the skin. The second procedure is tumescent anesthesia. In this procedure, the anesthetic in diluted form is introduced into the subcutaneous tissue. Both procedures are used in surgery and are standard methods of local anesthesia.
Timeline
- Start
- 2025-09-04
- Primary completion
- 2026-09-30
- Completion
- 2027-09-30
Publications
- Background Hanke C, Dent M. Beyond Liposuction: Evolving Applications for Tumescent Anesthesia. J Drugs Dermatol. 2022 Jan 1;21(1):86-89. doi: 10.36849/JDD.2022.6279.
- Background Uttamani RR, Venkataram A, Venkataram J, Mysore V. Tumescent Anesthesia for Dermatosurgical Procedures Other Than Liposuction. J Cutan Aesthet Surg. 2020 Oct-Dec;13(4):275-282. doi: 10.4103/JCAS.JCAS_192_19.
- Background Dessily M, Dziubeck M, Chahidi E, Simonelli V. The SiLaC procedure for pilonidal sinus disease: long-term outcomes of a single institution prospective study. Tech Coloproctol. 2019 Dec;23(12):1133-1140. doi: 10.1007/s10151-019-02119-2. Epub 2019 Nov 26.
- Background Horesh N, Meiri H, Anteby R, Zager Y, Maman R, Carter D, Meyer R, Nachmany I, Ram E. Outcomes of Laser-Assisted Closure (SiLaC) Surgery for Chronic Pilonidal Sinus Disease. J Laparoendosc Adv Surg Tech A. 2023 Jun;33(6):556-560. doi: 10.1089/lap.2022.0567. Epub 2023 Mar 9.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Epinephrine | Other / unclassified | 1 mg/ml | Other |
| Comparator | Lidocaine | Other / unclassified | 2 % | Other |
| Comparator | sodium bicarbonate | Diagnostic / imaging agent | 5 ml | Other |