drugset / Trial / NCT07528118
Comparison of Acetaminophen With Aminophylline and Aminophylline With Dexamethasone for Prophylaxis of PDPH in Patients With History of PDPH.
RandomizedParallel-groupSingle-blindPrevention
Summary
It is hypothesized that there is a difference between intravenously administered aminophylline with intravenous acetaminophen and intravenously administered aminophylline with dexamethasone for prevention of and reducing severity of PDPH.
Timeline
- Start
- 2023-08-01
- Primary completion
- 2024-06-02
- Completion
- 2024-07-08
Publications
- Background Jabalameli, M., Hashemi, S.T., Asadpoor, S., 2019. The efficacy of prophylactic intravenous aminophylline, paracetamol or aminophylline and paracetamol in prevention of post spinal headache in lower extremity surgeries compared to the control group. Tehran Univ. Medical J., 77(5), pp.294-300.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 1000 mg | Intravenous |
| Subject | Dexamethasone | Small molecule | 0.1 mg/kg | Intravenous |
| Background | Aminophylline | Small molecule | 100 mg | Intravenous |
Indications
No indication recorded.