Propofol-sevoflurane Induction for Pediatric Nasotracheal Intubation.
Summary
Pediatric anesthesia differs significantly from adult anesthesia due to physiological differences and increased sensitivity to anesthetic agents. In surgeries requiring nasotracheal intubation, such as dental and maxillofacial procedures, achieving optimal intubation conditions while minimizing pharmacological exposure is of considerable importance. The combination of propofol and sevoflurane is frequently preferred in pediatric anesthesia because it provides rapid induction and stable hemodynamic conditions. Therefore, this randomized controlled trial aims to evaluate nasotracheal intubation conditions following propofol-sevoflurane induction with reduced pharmacological exposure in pediatric patients. The study is expected to contribute to clinical practice by enhancing patient safety while reducing anesthetic drug use.
Timeline
- Start
- 2026-07-01
- Primary completion
- 2026-08-01
- Completion
- 2026-08-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | Intravenous |
| Comparator | Rocuronium | Other / unclassified | 0.3 mg/kg | Intravenous |
| Background | Propofol | Small molecule | 2.5 mg/kg | Intravenous |
| Background | Sevoflurane | Other / unclassified | 8 % | Inhaled |
Indications
No indication recorded.