Drugs / acebutolol
acebutolol
also known as
Acebut hcl · Acebutolol 200 mg capsule (Acetanol) · Acebutolol hcl · ACEBUTOLOL HYDROCHLORIDE · Acetanol · B 17803A · C07AB04 · IL-17803A · +8 more
Small molecule targets ADRB1 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | SECTRAL | — | 1984-12-28 | fda.gov ↗ |
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT00000522 | Aug 1985 → May 1994 | heart disorder, hypertensive disorder | University of Minnesota | Completed | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT05585125 | Feb 2024 → Jul 2026 overdue | diastolic heart failure | Weill Medical College of Cornell University | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT05019027 | Jan 2024 → Mar 2026 overdue | amyloidosis, heart disorder | Weill Medical College of Cornell University | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT01514019 | Jan → May 2012 | — | In-Jin Jang, MD, PhD | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00578617 | Sep 2006 → Feb 2009 | atrial fibrillation | Mayo Clinic | Completed | No outcome recorded |
| Comparator or background therapy5 trials | ||||||
| Phase 3 | NCT01743885 Comparator | Nov 2012 → Jun 2015 | hemangioma | University Hospital, Montpellier | Terminated | No outcome recorded |
| Phase 4 | NCT04767061 Comparator | Apr 2021 → Apr 2022 | diastolic heart failure | Weill Medical College of Cornell University | Completed | No outcome recorded |
| Phase 4 | NCT04757584 Comparator | Apr 2021 → Apr 2023 | diastolic heart failure | Weill Medical College of Cornell University | Completed | No outcome recorded |
| — | NCT00911508 Comparator | Nov 2009 → Dec 2017 | atrial fibrillation | Mayo Clinic | Completed | No outcome recorded |
| — | NCT00684489 Comparator | Sep 2003 → Mar 2005 | essential hypertension | Medical University of South Carolina | Completed | No outcome recorded |
Evidence & citations 21 cited values
Every value below carries the sentence it was read from. 11 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | acebutolol | “Other names:
acebutolol, atenolol, betaxolol, bisoprolol, carvedilol, labetalol, metoprolol, metoprolol succinate, metoprolol tartrate, nadolol, nebivolol, propranolol,...” NCT05585125 ↗9“Other Names: * acebutolol * atenolol * betaxolol * bisoprolol * carvedilol * labetalol * metoprolol succinate * metoprolol tartrate * nadolol * nebivolol * penbutolol *...” NCT05019027 ↗ “Propranolol 40-80mg, Acebutolol 200-300mg, Carvedilol 6.25-25mg” NCT00911508 ↗ “propranolol, timolol, acebutolol, penbutolol pindolol” NCT00684489 ↗ “Acebutolol 200mg” NCT00578617 ↗ “acebutolol” NCT04767061 ↗ “acebutolol” NCT04757584 ↗ |
| Known as | Acebut hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | Acebutolol 200 mg capsule (Acetanol) | “Acebutolol 200 mg capsule (Acetanol®)” NCT01514019 ↗ |
| Known as | Acebutolol hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | ACEBUTOLOL HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | Acetanol | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | B 17803A | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | C07AB04 | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | IL-17803A | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | M& | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | M&B 17803A | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | Neptal | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | NSC-757412 | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | Prent | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | Sectral | “Acebutolol (Sectral:oral solution)” NCT01743885 ↗ |
| Known as | Sectral 200 | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Known as | Sectral 400 | ChEMBL registry synonym — accepted as the source's own label CHEMBL642 ↗ |
| Action | Inhibit | “Beta-1 adrenergic receptor antagonist” CHEMBL642 ↗ |
| Modality | Small molecule | — CHEMBL642 ↗ |
| Route | Oral | “Acebutolol (Sectral:oral solution)” NCT01743885 ↗ |
| Target | ADRB1 | “Beta-1 adrenergic receptor antagonist” CHEMBL642 ↗ |