drugset / Trial / NCT04767061
Impact of Beta-blockers on Physical Function in HFpEF
Phase 4
Completed
9 enrolled
Weill Medical College of Cornell University
The New York Community Trust · collab
RandomizedCrossoverOpen-labelOther
Summary
The purpose of this study is to understand the impact of beta-blockers on physical function in older adults with heart failure. We will achieve this objective by conducting N-of-1 trials. N-of-1 trials are personalized experiments that test different treatment options in an individual patient.
Timeline
- Start
- 2021-04-01
- Primary completion
- 2022-04-28
- Completion
- 2023-04-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atenolol | Other / unclassified | — | — |
| Comparator | Bisoprolol | Other / unclassified | — | — |
| Comparator | Carvedilol | Other / unclassified | — | — |
| Comparator | Labetalol | Small molecule | — | — |
| Comparator | Metoprolol | Other / unclassified | — | — |
| Comparator | Nadolol | Unknown | — | — |
| Comparator | Nebivolol | Other / unclassified | — | — |
| Comparator | Pindolol | Small molecule | — | — |
| Comparator | Propranolol | Small molecule | — | — |
| Comparator | acebutolol | Small molecule | — | — |
| Comparator | betaxolol | Small molecule | — | — |
| Comparator | penbutolol | Small molecule | — | — |
| Comparator | sotalol | Small molecule | — | — |