Drugs / Lactobacillus rhamnosus GG
last change Jul 2026 re-read 2 minutes ago

Lactobacillus rhamnosus GG

Other / unclassified

Developed for
spinal cord injury · asthma · atopic eczema · diarrheal disease · food allergy · gastroenteritis · hyperbilirubinemia · perennial allergic rhinitis
+8 more · periapical periodontitis · post-traumatic stress disorder · pulpitis · type 1 diabetes mellitus · urinary tract infection · vernal keratoconjunctivitis · neonatal sepsis · perinatal necrotizing enterocolitis
Investigated by
Medstar Health Research Institute · Children's National Research Institute · Georgetown University · Patient-Centered Outcomes Research Institute · Brown University · Campus-Bio-Medico University
+24 more · Children's Hospital Medical Center, Cincinnati · Chinese University of Hong Kong · Columbia University · Dow University of Health Sciences · Fargo VA Medical Center · Medical University of Warsaw · Northwestern University · Norwegian University of Science and Technology · Quaid-e-Azam Medical College · St. Olavs Hospital · Tine · United States Department of Defense · University of California, Davis · University of Colorado, Boulder · University of Colorado, Denver · University of Genova · University of Michigan · University of New Mexico · University of Padova · University of Pittsburgh Medical Center · University of Utah · VA Eastern Colorado Health Care System · Washington University School of Medicine · Wayne State University

Trials 13 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT07643974 Jun 2026 → Sep 2027 expected multiple sclerosis, spina bifida, spinal cord injury, urinary bladder disorder +1 Medstar Health Research Institute Not yet recruiting No outcome recorded
Phase 11 trial
Phase 1 NCT00748748 Feb 2010 → Apr 2012 diarrheal disease Fargo VA Medical Center Completed No outcome recorded
Phase 25 trials
Phase 2 NCT07102836 Aug 2025 → Feb 2026 overdue hyperbilirubinemia Quaid-e-Azam Medical College Recruiting No outcome recorded
Phase 2 NCT05230511 Jun 2022 → Jul 2026 overdue spinal cord injury Medstar Health Research Institute Recruiting No outcome recorded
Phase 2 NCT04150380 Aug 2020 → Dec 2025 post-traumatic stress disorder VA Eastern Colorado Health Care System Completed No outcome recorded
Phase 2 NCT02748317 Jan 2016 → Oct 2018 Medstar Health Research Institute Completed No outcome recorded
Phase 2 NCT02748356 Jan 2016 → Oct 2018 Medstar Health Research Institute Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT01773967 Jul 2014 → Aug 2018 gastroenteritis Washington University School of Medicine Completed No outcome recorded
Phase 2/3 NCT00445120 Mar 2007 → Sep 2008 vernal keratoconjunctivitis Campus-Bio-Medico University Completed No outcome recorded
Phase 41 trial
Phase 4 NCT03032354 Jul 2017 → Dec 2018 type 1 diabetes mellitus Medical University of Warsaw Unknown No outcome recorded
Phase not applicable3 trials
NCT07270159 Jun → Oct 2025 periapical periodontitis, pulpitis Dow University of Health Sciences Completed No outcome recorded
NCT05165329 Nov 2021 → Sep 2024 food allergy Chinese University of Hong Kong Unknown No outcome recorded
NCT00159523 Dec 2003 → Sep 2007 asthma, atopic eczema, perennial allergic rhinitis Norwegian University of Science and Technology Completed No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00756262 Comparator Mar 2003 → Jul 2012 Tufts Medical Center Terminated No outcome recorded
Phase 41 trial
Phase 4 NCT07296718 Comparator May → Nov 2023 neonatal sepsis, perinatal necrotizing enterocolitis Madiha, MPhil Completed No outcome recorded
Phase not applicable1 trial
NCT02807246 Comparator Dec 2014 → Dec 2015 hyperbilirubinemia Karadeniz Technical University Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 20 sources stand behind the page.

FieldValueCited text
Known as Lactobacillus rhamnosus GG “Participants received a 5-day course of Lactobacillus rhamnosus GG at a dose of 1×1010 colony-forming units twice daily or matching placebo.” PMID 30462938 Nov 2018
15

“The probiotic milk contained Lactobacillus rhamnosus GG, L. acidophilus La-5 and Bifidobacterium animalis subsp. lactis Bb-12.” PMID 20545688 Jun 2010

“probiotic Lactobacillus rhamnosus GG (LGG) for the reduction or elimination of intestinal colonization by VRE.” PMID 26014940 May 2015

“PROBIOTIC: The probiotic to be used is Lactobacillus rhamnosus GG, supplied as a freeze-dried powder.” NCT05165329

“Maflor®, Lactobacillus rhamnosus GG 109 CFU, Mamsel Pharmaceuticals, Turkey” NCT02807246

“a probiotic paste consisting of Lactobacillus rhamnosus GGNCT07270159

“10\^10 Lactobacillus rhamnosus GG per capsule” NCT00748748

Lactobacillus rhamnosus GGNCT02748356

NCT07102836

NCT04150380

NCT02748317

NCT07296718

NCT03032354

NCT05230511

NCT00445120

NCT07643974

Known as ATCC strain 53103 “Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766)” NCT04150380
Known as CRMTS #11272 “Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766)” NCT04150380
Known as Culturelle “Lactobacillus GG or CulturelleNCT00756262
Known as Culturelle GG “Participants will receive the Lactobacillus (Culturelle GG, 20 billion live organisms for adults and 10 billion live organisms for children \<18 years of age)” NCT02748356
Known as LGG “Here we present the methods of a large, rigorous, randomised, double-blind placebo-controlled study to assess the effectiveness and side effect profile of Lactobacillus...” PMID 28947466 Sep 2017
2

“The probiotic bacteria included Lactobacillus rhamnosus GG (LGG), Bifidobacterium animalis subsp. lactis Bb-12 and Lactobacillus acidophilus La-5.” PMID 28837002 Aug 2017

“Lactobacillus rhamnosus GG (LGG; ATCC53103), a probiotic shown to have anti-inflammatory and immunoregulatory effects” NCT04150380

Known as PTS #3766 “Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766)” NCT04150380
Modality Other / unclassified “The probiotic bacteria included Lactobacillus rhamnosus GG (LGG), Bifidobacterium animalis subsp. lactis Bb-12 and Lactobacillus acidophilus La-5.” PMID 28837002 Aug 2017
Route Oral “a subset of 278 pregnant mothers was randomized to drink milk with or without probiotic bacteria during and after pregnancy” PMID 33240830 Nov 2020