Ferrous Sulfate

also known as Ferrous fumarate · ferrous sulphate · ferrous succinate · Fer-In-Sol · Dried Ferrous Sulfate · Eisen-II-Sulfat · FeFum · Ferli-6 · +12 more

Diagnostic / imaging agent

Developed for: iron deficiency anemia · anemia · disorder of iron metabolism and transport · pregnancy disorder · chronic kidney disease · Crohn disease · heart failure · inflammatory bowel disease
+26 more
· iron metabolism disease · ulcerative colitis · anemia due to chronic disorder · aregenerative anemia · craniosynostosis · hereditary hemorrhagic telangiectasia · insomnia · lead poisoning · schistosomiasis · systolic heart failure · X-linked erythropoietic protoporphyria · chemotherapy-induced toxicity · chronic renal failure syndrome · cognitive impairment with or without cerebellar ataxia · colon carcinoma · colorectal carcinoma · cystic fibrosis · deficiency anemia · diastolic heart failure · microcytic anemia · myocardial infarction · periodic limb movement disorder · post-surgical hypoinsulinemia · postgastrectomy syndrome · restless legs syndrome · uterine disorder
Investigated by: Baylor College of Medicine · GlaxoSmithKline · Rockwell Medical Technologies, Inc. · University of Ulm · Watson Pharmaceuticals · Weill Medical College of Cornell University
+78 more
· Academic Medical Center - University of Amsterdam · Academy of Finland · AdventHealth · Ain Shams Maternity Hospital · Akebia Therapeutics · Astellas Pharma Inc · Autism Treatment Network · Build Healthy India Movement · Centers for Disease Control and Prevention · Chengdu Maternal and Children's Health Care Hospital · Children's Hospital of Philadelphia · Cornell University · Crohn's and Colitis Foundation · DBL -Institute for Health Research and Development · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · FHI 360 · Federal University of Goiás · Federal University of São Paulo · Fluminense Federal University · Ghana Health Services · Goiania Municipal Health Department · Health Resources and Services Administration (HRSA) · Hospital de Clinicas de Porto Alegre · Icahn School of Medicine at Mount Sinai · Imperial College London · Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri · Iowa State University · Istanbul University - Cerrahpasa · Kyntra Bio · Leiden University Medical Center · Liverpool University Hospitals NHS Foundation Trust · Luzerner Kantonsspital · Maastricht University Medical Center · Martini Hospital Groningen · Massachusetts General Hospital · Ministry of Health, Brazil · Ministry of Science and Technology, India · National Cardiovascular Center Harapan Kita Hospital Indonesia · National Heart, Lung, and Blood Institute (NHLBI) · National Institute for Health and Welfare, Finland · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Netherlands Overseas Agency · Pakistan Air Force (PAF) Hospital Islamabad · Peterborough Hospitals Hip Fracture Project · Peterborough and Stamford Hospitals NHS Foundation Trust · Phramongkutklao College of Medicine and Hospital · Pierre Fabre Laboratories · Prince of Songkla University · Queen Mary University of London · Radboud University Medical Center · Sao Jose do Rio Preto Medical School · Shahida Islam Medical Complex · Shengjing Hospital · Southern Illinois University · Southern Medical University, China · Stony Brook University · Sunnybrook Health Sciences Centre · Swiss Federal Institute of Technology · Swiss National Science Foundation · Swiss Tropical & Public Health Institute · Texas Tech University · The Emmes Company, LLC · The Thai Society of Hematology · The University of Texas Health Science Center, Houston · The University of Texas Medical Branch, Galveston · Thrasher Research Fund · Unity Health Toronto · University Health Network, Toronto · University Hospital, Montpellier · University Medical Center Groningen · University of Child Health Sciences and Children's Hospital, Lahore · University of Colorado, Denver · University of Missouri-Columbia · University of North Texas Health Science Center · all 84 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	FOLVRON	—	1946-08-13	fda.gov ↗

Trials 59

today

US approved 1946

194519461947194819491950195119521953195419551956195719581959196019611962196319641965196619671968196919701971197219731974197519761977197819791980198119821983198419851986198719881989199019911992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028202920302031

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 14 trials
Phase 1	NCT02767128	Apr 2016	IRIDA syndrome	Rockwell Medical Technologies, Inc.	Completed	No outcome recorded
Phase 1	NCT02327546	Dec 2014	—	Akebia Therapeutics	Completed	No outcome recorded
Phase 1	NCT01757119	Jan 2013 → Mar 2014	iron deficiency anemia	Pierre Fabre Laboratories	Completed	No outcome recorded
Phase 1	NCT01762995	Dec 2012 → Mar 2013	HIV infectious disease	ViiV Healthcare	Completed	No outcome recorded
Phase 29 trials · 2 missed
Phase 2	NCT05544513	Aug 2022 → Dec 2026 expected	anemia due to chronic disorder, chronic kidney disease, immune dysregulation, neurodevelopmental defects, and colitis, iron deficiency anemia	Fluminense Federal University	Active not recruiting	No outcome recorded
Phase 2	NCT03457701	Jul 2019 → Jul 2022	anemia	GlaxoSmithKline	Completed	Missed primary
Phase 2	NCT03481790	Sep 2017 → Mar 2018	iron deficiency anemia	Ain Shams Maternity Hospital	Completed	No outcome recorded
Phase 2	NCT02905981	Jan 2017 → Mar 2018	IRIDA syndrome	Rockwell Medical Technologies, Inc.	Terminated	No outcome recorded
Phase 2	NCT01745497	Dec 2012 → Aug 2015	autism spectrum disorder, insomnia	University of Colorado, Denver	Completed	No outcome recorded
Phase 2	NCT01414075	Jul 2011 → Jan 2013	anemia	Kyntra Bio	Completed	Missed primary
Phase 2	NCT00374790	Oct 2006 → May 2008	lead poisoning	Cornell University	Completed	No outcome recorded
Phase 2	NCT00450177	Jan 2006 → Dec 2007	aregenerative anemia	Weill Medical College of Cornell University	Completed	No outcome recorded
Phase 2	NCT00152841	Jun 2002 → Feb 2009	Crohn disease, anemia, ulcerative colitis	University Health Network, Toronto	Terminated	No outcome recorded
Phase 2/33 trials · 1 met primary
Phase 2/3	NCT02998697	Jan → Oct 2016	iron deficiency anemia, systolic heart failure	National Cardiovascular Center Harapan Kita Hospital Indonesia	Completed	Met primary
Phase 2/3	NCT00386126	Aug 2006 → ?	anemia, heart failure	Hospital de Clinicas de Porto Alegre	Unknown	No outcome recorded
Phase 2/3	NCT00223977	Dec 2003 → Nov 2004	iron deficiency anemia	Watson Pharmaceuticals	Completed	No outcome recorded
Phase 310 trials · 2 missed
Phase 3	NCT07661602	Jul → Aug 2026 overdue	anemia	Southern Medical University, China	Not yet recruiting	No outcome recorded
Phase 3	NCT07708025	Sep 2025 → Feb 2026	anemia, heart failure	University of Porto	Completed	No outcome recorded
Phase 3	NCT07267975	Jan → Mar 2025	iron deficiency anemia	University of Child Health Sciences and Children's Hospital, Lahore	Completed	No outcome recorded
Phase 3	NCT06321887	Oct 2023 → Oct 2024	inflammatory bowel disease, iron deficiency anemia	Liverpool University Hospitals NHS Foundation Trust	Unknown	No outcome recorded
Phase 3	NCT04371536	Jul 2021 → Feb 2022	iron deficiency anemia	Baylor College of Medicine	Completed	No outcome recorded
Phase 3	NCT04130828	Jan 2020 → Jan 2022	iron deficiency anemia	Prince of Songkla University	Completed	No outcome recorded
Phase 3	NCT03725384	Jan 2019 → Jan 2022	iron deficiency anemia	Sunnybrook Health Sciences Centre	Completed	No outcome recorded
Phase 3	NCT00364104	Mar 2007 → Dec 2008	iron metabolism disease	The University of Texas Health Science Center, Houston	Completed	Missed primary
Phase 3	NCT00136266	Mar → Dec 2005	iron deficiency anemia	Centers for Disease Control and Prevention	Completed	Missed primary
Phase 3	NCT00919230	Jul 2004 → Jul 2009	—	Peterborough and Stamford Hospitals NHS Foundation Trust	Completed	No outcome recorded
Phase 412 trials · 1 met primary
Phase 4	NCT06492512	May 2025 → Jul 2028 expected	iron deficiency anemia, pregnancy disorder	Southern Illinois University	Recruiting	No outcome recorded
Phase 4	NCT06238895	Mar 2024 → Nov 2025	iron deficiency anemia, iron metabolism disease	Luzerner Kantonsspital	Completed	No outcome recorded
Phase 4	NCT05456932	Aug 2022 → Aug 2023	disorder of iron metabolism and transport, inflammatory bowel disease, iron deficiency anemia	Leiden University Medical Center	Unknown	No outcome recorded
Phase 4	NCT05278793	Jan → Dec 2022	iron deficiency anemia, pregnancy disorder	Martini Hospital Groningen	Unknown	No outcome recorded
Phase 4	NCT04975074	Jul → Dec 2021	iron deficiency anemia	Shengjing Hospital	Unknown	No outcome recorded
Phase 4	NCT05007899	Dec 2020 → Jun 2022	iron deficiency anemia	Baylor College of Medicine	Completed	No outcome recorded
Phase 4	NCT04594070	Oct 2020 → Jan 2024	iron deficiency anemia, pregnancy disorder	The University of Texas Medical Branch, Galveston	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT03991169	Apr 2019 → Dec 2028 expected	chronic kidney disease	Weill Medical College of Cornell University	Recruiting	No outcome recorded
Phase 4	NCT03359447	Aug 2017 → Mar 2019	iron deficiency anemia	Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri	Unknown	No outcome recorded
Phase 4	NCT01991314	Dec 2011 → Jun 2015	Crohn disease, ulcerative colitis	Queen Mary University of London	Completed	No outcome recorded
Phase 4	NCT00488579	May → Dec 2007	pregnancy disorder	National Institute for Health and Welfare, Finland	Completed	No outcome recorded
Phase 4	NCT00224068	May 2002 → Dec 2003	anemia	Watson Pharmaceuticals	Completed	Met primary

Phase not applicable21 trials · 1 missed
—	NCT07657455	Sep → Dec 2026 expected	iron deficiency anemia	Pakistan Air Force (PAF) Hospital Islamabad	Not yet recruiting	No outcome recorded
—	NCT07816601	May 2026 → Nov 2027 expected	iron deficiency anemia	AdventHealth	Recruiting	No outcome recorded
—	NCT07263529	Sep 2025 → Jan 2026 overdue	disorder of iron metabolism and transport	Istanbul University - Cerrahpasa	Recruiting	No outcome recorded
—	NCT07014371	Jun 2025 → Dec 2027 expected	iron deficiency anemia	Phramongkutklao College of Medicine and Hospital	Recruiting	No outcome recorded
—	NCT07340450	Feb → Aug 2025	—	Shahida Islam Medical Complex	Completed	No outcome recorded
—	NCT05233956	Oct 2023 → Dec 2026 expected	anemia	FHI 360	Active not recruiting	No outcome recorded
—	NCT05423249	Aug 2022 → Nov 2024	disorder of iron metabolism and transport	Stony Brook University	Completed	No outcome recorded
—	NCT03231085	Oct 2017 → Apr 2024	craniosynostosis	University Hospital, Montpellier	Completed	No outcome recorded
—	NCT02979249	Dec 2016 → Jul 2019	X-linked erythropoietic protoporphyria	Icahn School of Medicine at Mount Sinai	Completed	No outcome recorded
—	NCT02839096	Jun 2016 → Jun 2019	iron deficiency anemia	University of Missouri-Columbia	Terminated	No outcome recorded Stop: Business
—	NCT03156725	May → Sep 2014	disorder of iron metabolism and transport	Iowa State University	Completed	No outcome recorded
—	NCT01908543	Jul 2013 → Jul 2015	hereditary hemorrhagic telangiectasia	Imperial College London	Terminated	No outcome recorded
—	NCT01634945	Apr 2012 → May 2013	anemia	Swiss Federal Institute of Technology	Completed	Missed primary
—	NCT01355263	Jul 2011 → Feb 2012	disorder of iron metabolism and transport	Chengdu Maternal and Children's Health Care Hospital	Completed	No outcome recorded
—	NCT01129843	May 2010 → Jan 2011	iron deficiency anemia	Build Healthy India Movement	Completed	No outcome recorded
—	NCT00992823	Mar 2006 → Feb 2007	anemia	Sao Jose do Rio Preto Medical School	Completed	No outcome recorded
—	NCT00276224	Sep 2005 → Apr 2006	anemia, schistosomiasis	DBL -Institute for Health Research and Development	Completed	No outcome recorded
—	NCT00301054	Jun 2005 → Apr 2006	anemia	Ghana Health Services	Completed	No outcome recorded
—	NCT00701246	Apr 2005 → Mar 2006	anemia	Federal University of Goiás	Completed	No outcome recorded
—	NCT00457990	Apr 2002 → Dec 2005	anemia of prematurity, disorder of iron metabolism and transport, neurodevelopmental disorder	University of Ulm	Completed	No outcome recorded
—	NCT00458068	Jun 1996 → Sep 1999	anemia of prematurity, iron deficiency anemia	University of Ulm	Completed	No outcome recorded

Comparator or background therapy100 trials
Phase 0	NCT05349630 Comparator	Mar 2028 → Dec 2029 expected	—	University of Colorado, Denver	Not yet recruiting	No outcome recorded
Phase 0	NCT02005588 Comparator	Dec 2013 → Jun 2015	iron deficiency anemia	Cairo University	Completed	No outcome recorded
Phase 1	NCT00535561 Comparator	Jun → Sep 2007	hypothyroidism, iron deficiency anemia	Duzce University	Completed	No outcome recorded
Phase 1	NCT00867867 Comparator	Oct 2003 → Jun 2008	Helicobacter pylori infectious disease	International Centre for Diarrhoeal Disease Research, Bangladesh	Completed	No outcome recorded
Phase 1/2	NCT03484845 Comparator	Nov 2018 → Dec 2019	iron deficiency anemia	Assiut University	Unknown	No outcome recorded
Phase 1/2	NCT07110935 Comparator	Sep 2018 → Feb 2019	—	Federal Teaching Hospital Abakaliki	Completed	No outcome recorded
Phase 2	NCT05299411 Comparator	Apr 2023 → Mar 2025	chemotherapy-induced toxicity, colon carcinoma	Korea University Guro Hospital	Unknown	No outcome recorded
Phase 2	NCT05340465 Comparator	Nov 2022 → Jan 2027 expected	disorder of iron metabolism and transport, iron deficiency anemia	University of Washington	Recruiting	No outcome recorded
Phase 2	NCT03891277 Comparator	Apr 2019 → Oct 2021	cerebral infarction, cognitive impairment with or without cerebellar ataxia, iron deficiency anemia, transient ischemic attack +1	Beijing Tiantan Hospital	Unknown	No outcome recorded
Phase 2	NCT03759353 Comparator	Jan → Oct 2018	iron deficiency anemia	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT03232554 Comparator	Jun 2017 → Dec 2018	iron deficiency anemia	Peking Union Medical College Hospital	Unknown	No outcome recorded
Phase 2	NCT02499354 Comparator	Aug 2014 → Sep 2021	iron deficiency anemia, restless legs syndrome	Auerbach Hematology Oncology Associates P C	Completed	No outcome recorded
Phase 2	NCT01670955 Comparator	Dec 2012 → Jun 2013	anemia	Lagos State University	Completed	No outcome recorded
Phase 2	NCT01438372 Comparator	Nov 2011 → Feb 2012	inflammatory bowel disease, iron deficiency anemia	Wayne State University	Withdrawn	No outcome recorded Stop: Enrollment
Phase 2/3	NCT03940430 Comparator	Sep → Nov 2018	iron deficiency anemia	yasmin gamal el gendy	Completed	No outcome recorded
Phase 2/3	NCT00929409 Comparator	Jun 2009 → Jul 2010	iron deficiency anemia, postpartum depression, puerperal disorder	Norwegian University of Science and Technology	Terminated	No outcome recorded Stop: Enrollment
Phase 3	NCT07556731 Comparator	May 2026 → May 2027 expected	iron deficiency anemia, iron metabolism disease	Hospital General de Mexico	Not yet recruiting	No outcome recorded
Phase 3	NCT07381426 Comparator	Feb → Dec 2026 expected	anemia	Dhaka Medical College	Recruiting	No outcome recorded
Phase 3	NCT06884280 Comparator	Nov 2025 → Oct 2027 expected	iron deficiency anemia	Hull University Teaching Hospitals NHS Trust	Recruiting	No outcome recorded
Phase 3	NCT06366698 Comparator	Nov 2023 → Dec 2025	iron deficiency anemia	Arrowhead Regional Medical Center	Unknown	No outcome recorded
Phase 3	NCT05784870 Comparator	Feb 2023 → Dec 2024	aregenerative anemia	Zhongnan Hospital	Unknown	No outcome recorded
Phase 3	NCT05462704 Comparator	Jan 2023 → Mar 2027 expected	iron deficiency anemia, pregnancy disorder	Women and Infants Hospital of Rhode Island	Recruiting	No outcome recorded
Phase 3	NCT05304442 Comparator	Sep 2022 → Mar 2025 overdue	iron deficiency anemia, uterine disorder	Baylor College of Medicine	Recruiting	No outcome recorded
Phase 3	NCT05126901 Comparator	Nov 2021 → Jun 2024	iron deficiency anemia	Shield Therapeutics	Completed	No outcome recorded
Phase 3	NCT04976179 Comparator	Aug 2021 → Apr 2023	iron deficiency anemia	University of Lagos, Nigeria	Completed	Missed primary
Phase 3	NCT04253626 Comparator	Jan 2021 → Jul 2024	iron deficiency anemia, pregnancy disorder	Stanford University	Completed	Met primary
Phase 3	NCT03957057 Comparator	Sep 2020 → Apr 2022	deficiency anemia, iron deficiency anemia	University Medical Centre Ljubljana	Completed	No outcome recorded
Phase 3	NCT04087993 Comparator	May → Dec 2020	iron deficiency anemia	Dr. Frank Behrens	Withdrawn	No outcome recorded Stop: Enrollment
Phase 3	NCT03523117 Comparator	Jan 2019 → Dec 2020	iron deficiency anemia	American Regent, Inc.	Completed	No outcome recorded
Phase 3	NCT03817957 Comparator	Sep 2018 → Dec 2023	iron deficiency anemia	Prof. Dr. Frank Behrens	Completed	No outcome recorded
Phase 3	NCT03212781 Comparator	Jun → Sep 2016	anemia	Assiut University	Completed	No outcome recorded
Phase 3	NCT03378791 Comparator	Dec 2015 → Oct 2017	iron deficiency anemia	Hatem AbuHashim	Completed	No outcome recorded
Phase 3	NCT02541708 Comparator	Sep 2015 → Apr 2018	iron deficiency anemia	Ifakara Health Institute	Unknown	Met primary
Phase 3	NCT03106454 Comparator	Aug 2014 → Jan 2024	anovulation	University of Southern California	Completed	No outcome recorded
Phase 3	NCT01656434 Comparator	Nov 2012 → Feb 2014	—	Organon and Co	Terminated	No outcome recorded Stop: Business
Phase 3	NCT01155375 Comparator	Oct 2011 → Jun 2014	iron deficiency anemia	AMAG Pharmaceuticals, Inc.	Terminated	No outcome recorded Stop: Enrollment
Phase 3	NCT01131624 Comparator	May 2010 → May 2014	anemia	Vifor Pharma	Completed	No outcome recorded
Phase 3	NCT00994318 Comparator	Dec 2009 → Feb 2013	chronic kidney disease, iron deficiency anemia	Vifor Pharma	Completed	Met primary
Phase 3	NCT00982007 Comparator	Sep 2009 → Mar 2011	iron deficiency anemia	American Regent, Inc.	Completed	No outcome recorded
Phase 3	NCT00704353 Comparator	Jun 2008 → Jul 2009	anemia	American Regent, Inc.	Completed	No outcome recorded
Phase 3	NCT00354484 Comparator	May → Dec 2006	—	American Regent, Inc.	Completed	No outcome recorded
Phase 3	NCT00317239 Comparator	May 2005 → Feb 2007	anemia	American Regent, Inc.	Completed	Met primary
Phase 3	NCT00395993 Comparator	May 2005 → Apr 2006	anemia	American Regent, Inc.	Completed	Met primary
Phase 3	NCT00396292 Comparator	Feb → Nov 2005	anemia	American Regent, Inc.	Completed	No outcome recorded
Phase 3	NCT00236977 Comparator	Aug 2003 → Oct 2004	anemia	American Regent, Inc.	Completed	Met primary
Phase 3	NCT00236964 Comparator	Feb 2001 → May 2002	anemia	American Regent, Inc.	Completed	Mixed
Phase 4	NCT07659184 Comparator	Oct 2026 → Sep 2028 expected	anemia	University of Aarhus	Not yet recruiting	No outcome recorded
Phase 4	NCT07414199 Comparator	Jan → Jun 2026 overdue	iron deficiency anemia	Children's Hospital of Orange County	Not yet recruiting	No outcome recorded
Phase 4	NCT07605676 Background	Jan → Aug 2026 overdue	iron deficiency anemia	Cairo University	Recruiting	No outcome recorded
Phase 4	NCT05060731 Comparator	Sep 2025 → Dec 2027 expected	anemia	University of Pecs	Not yet recruiting	No outcome recorded
Phase 4	NCT07053475 Comparator	Apr 2025 → Mar 2026	diastolic heart failure, disorder of iron metabolism and transport, iron deficiency anemia, systolic heart failure	Syed Hamza Mufarrih	Terminated	Met primary
Phase 4	NCT06830941 Comparator	Feb 2025 → Feb 2027 expected	anemia	Xie Jingyuan, MD	Not yet recruiting	No outcome recorded
Phase 4	NCT06176430 Comparator	Feb → Mar 2024	cerebral palsy, iron deficiency anemia	Shaheed Zulfiqar Ali Bhutto Medical University	Unknown	No outcome recorded
Phase 4	NCT05714007 Comparator	Aug 2023 → Dec 2025 overdue	anemia	Peking Union Medical College Hospital	Recruiting	No outcome recorded
Phase 4	NCT05691257 Background	Feb → Aug 2023	anemia, chronic kidney disease, heart failure	China-Japan Friendship Hospital	Unknown	No outcome recorded
Phase 4	NCT05708170 Comparator	Jan 2023 → Aug 2026 overdue	iron deficiency anemia	Liverpool Hope University	Not yet recruiting	No outcome recorded
Phase 4	NCT05047211 Comparator	Oct 2021 → Mar 2023	iron deficiency anemia	The University of Texas Medical Branch, Galveston	Completed	No outcome recorded
Phase 4	NCT04278651 Comparator	Sep 2021 → Aug 2026 overdue	iron deficiency anemia, pregnancy disorder	Thomas Jefferson University	Recruiting	No outcome recorded
Phase 4	NCT04608539 Comparator	May 2021 → Jun 2023	aregenerative anemia	Michael Kremke	Completed	No outcome recorded
Phase 4	NCT04610827 Comparator	Nov 2020 → Jun 2021	iron metabolism disease, periodic limb movement disorder, restless legs syndrome	Mayo Clinic	Terminated	No outcome recorded
Phase 4	NCT04205266 Comparator	Feb 2020 → Jan 2025	iron deficiency anemia	Thomas Jefferson University	Unknown	No outcome recorded
Phase 4	NCT03830034 Comparator	Feb → Oct 2019	iron deficiency anemia	Ain Shams University	Unknown	No outcome recorded
Phase 4	NCT04435574 Comparator	Sep 2018 → Apr 2019	iron deficiency anemia	Cairo University	Completed	No outcome recorded
Phase 4	NCT03524651 Comparator	May 2018 → Jan 2021	iron deficiency anemia	Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.	Completed	No outcome recorded
Phase 4	NCT03438227 Comparator	Apr 2018 → Dec 2019	disorder of mineral absorption and transport, iron deficiency anemia	Indiana University	Completed	Met primary
Phase 4	NCT04267653 Comparator	Jan 2018	iron deficiency anemia	Assiut University	Completed	No outcome recorded
Phase 4	NCT03295851 Comparator	Nov 2017 → Mar 2019	anemia	Singapore General Hospital	Unknown	No outcome recorded
Phase 4	NCT03229954 Comparator	Aug 2017 → Apr 2019	postgastrectomy syndrome	Yonsei University	Unknown	No outcome recorded
Phase 4	NCT03188445 Comparator	Jul 2017 → Jun 2020	iron deficiency anemia	Pharmacosmos A/S	Completed	Met primary
Phase 4	NCT03010579 Comparator	Oct 2016 → Dec 2017	anemia, lymphoma	Peking University	Unknown	No outcome recorded
Phase 4	NCT02631668 Comparator	Jan 2016 → Dec 2018	iron deficiency anemia	Huashan Hospital	Completed	Met primary
Phase 4	NCT02825719 Background	Dec 2015 → Mar 2020	leiomyoma	Queen Mary Hospital, Hong Kong	Terminated	No outcome recorded
Phase 4	NCT03202615 Comparator	Sep 2015 → Aug 2018	microcytic anemia	Abdelwahed, Mai Mahmoud Mohamed, M.D.	Unknown	No outcome recorded
Phase 4	NCT01975272 Comparator	Mar 2015 → May 2018	—	Maastricht University Medical Center	Terminated	No outcome recorded
Phase 4	NCT02271997 Comparator	Dec 2014 → Jun 2017	disorder of iron metabolism and transport	Rijnstate Hospital	Completed	No outcome recorded
Phase 4	NCT02243735 Comparator	Nov 2014 → Nov 2019	anemia, colorectal carcinoma	Academic Medical Center - University of Amsterdam	Unknown	No outcome recorded
Phase 4	NCT02228902 Comparator	Aug 2014 → May 2015	disorder of mineral absorption and transport	Rijnstate Hospital	Completed	No outcome recorded
Phase 4	NCT02086968 Comparator	Jan 2014 → Jul 2016	iron deficiency anemia	American Regent, Inc.	Completed	No outcome recorded
Phase 4	NCT01904864 Comparator	Jul 2013 → Nov 2015	iron deficiency anemia	University of Texas Southwestern Medical Center	Completed	No outcome recorded
Phase 4	NCT01701310 Comparator	Apr 2012 → Dec 2014	anemia, colorectal carcinoma	Nottingham University Hospitals NHS Trust	Completed	No outcome recorded
Phase 4	NCT02620345 Background	Jan 2010 → Oct 2015	benign neoplasm of corpus uteri	Trieu, Nguyen Thi, M.D.	Completed	No outcome recorded
Phase 4	NCT00689793 Comparator	Nov 2008 → Oct 2010	disorder of iron metabolism and transport	University of Lausanne	Completed	No outcome recorded
Phase 4	NCT00746551 Comparator	Sep 2008 → Mar 2010	anemia, pregnancy disorder	Mahidol University	Completed	No outcome recorded
Phase 4	NCT00830037 Comparator	Aug 2008 → Nov 2014	chronic kidney disease, iron deficiency anemia	Indiana University	Terminated	Missed primary
Phase 4	NCT01078818 Comparator	May 2007 → May 2009	anemia	Fundación Canaria Rafael Clavijo para la Investigación Biomédica	Completed	Missed primary
Phase 4	NCT00223938 Comparator	Dec 2003 → Apr 2007	anemia	Sanofi	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT00224055 Comparator	Apr 2003 → Sep 2004	chronic renal failure syndrome, iron deficiency anemia	Watson Pharmaceuticals	Completed	Missed primary
Phase 4	NCT00224042 Comparator	Apr 2003 → May 2005	chronic renal failure syndrome, iron deficiency anemia	Watson Pharmaceuticals	Completed	No outcome recorded
—	NCT07366502 Comparator	Sep 2025 → Jul 2026 overdue	disorder of iron metabolism and transport, iron deficiency anemia	Medeni Şermet	Recruiting	No outcome recorded
—	NCT06742528 Comparator	Jan → Dec 2024 overdue	iron deficiency anemia	Arooj Khan	Recruiting	No outcome recorded
—	NCT05581420 Comparator	Jun 2022 → May 2025	inflammatory bowel disease	Leiden University Medical Center	Unknown	No outcome recorded
—	NCT05309499 Comparator	Dec 2021 → Sep 2025	iron deficiency anemia, myocardial infarction	Kazan State Medical University	Completed	No outcome recorded
—	NCT03777514 Comparator	Aug 2019 → Oct 2021	post-surgical hypoinsulinemia	Johns Hopkins University	Withdrawn	No outcome recorded
—	NCT02888171 Comparator	Sep 2016 → Feb 2019	anemia, chronic kidney disease, disorder of iron metabolism and transport	University of Alabama at Birmingham	Completed	Met primary
—	NCT02558725 Comparator	Apr 2015 → Feb 2016	pregnancy disorder	Assuta Hospital Systems	Unknown	No outcome recorded
—	NCT01628770 Comparator	May → Dec 2012	—	Dow University of Health Sciences	Completed	No outcome recorded
—	NCT01590134 Comparator	Mar → Dec 2012	—	Imperial College London	Unknown	No outcome recorded
—	NCT01755455 Comparator	Jun 2011 → Nov 2012	cystic fibrosis, iron deficiency anemia	Dartmouth-Hitchcock Medical Center	Completed	No outcome recorded
—	NCT00554814 Comparator	Nov 2007 → Nov 2008	disorder of iron metabolism and transport	Bledina	Suspended	No outcome recorded Stop: Enrollment
—	NCT00459225 Comparator	Apr 2007 → Jun 2013	anemia	Emory University	Withdrawn	No outcome recorded Stop: Enrollment

News releases announcing trial results or a regulatory action · 2

Date	Issuer	Release
2026-07-28	Shield Therapeutics	Results Shield Therapeutics - ACCRUFeR® Phase 3 pediatric trial published shieldtherapeutics.com ↗
2025-10-01	Shield Therapeutics	Results Shield Therapeutics - Positive efficacy and tolerance in pediatric trial shieldtherapeutics.com ↗ Clinically and statistically significant Hb improvements vs. baseline were observed across all groups (ferric maltol arms and ferrous sulfate arm (P<0.0001)

All press releases naming this drug 2 releases

Date	Issuer	Release
2026-07-28	Shield Therapeutics	Shield Therapeutics - ACCRUFeR® Phase 3 pediatric trial published shieldtherapeutics.com ↗
2025-10-01	Shield Therapeutics	Shield Therapeutics - Positive efficacy and tolerance in pediatric trial shieldtherapeutics.com ↗

Evidence & citations 23 cited values

Every value below carries the sentence it was read from. 162 sources stand behind the page.

Field	Value	Cited text
Known as	ferrous sulfate	“The purpose of the study was to compare the efficacy of oral iron (ferrous sulfate) plus erythropoietin to Iron Sucrose plus erythropoietin for managing anemia patients with...” NCT00236964 ↗ 91 “In the standard iron-folic acid supplementation group, participants diagnosed with iron deficiency anemia will receive ferrous sulfate tablets providing 60 mg of elemental iron...” NCT07661602 ↗ “Drug: FerroGrad by Abbott Dosage: one capsule three times /day containing150 mg of dried ferrous sulfate capsules (Ferrofol capsules, Eipico, Egypt), with placebo sachets.” NCT03202615 ↗ “oral ferrous iron preparations (ferrous sulfate), each providing 160 mg elemental iron once daily, administered on an empty stomatch with 200 mg vitamin c for 3 months.” NCT07366502 ↗ “either hydroxide polymaltose \[Ferrum Haussman®\] or ferrous sulfate \[Ferro Gradumet®\]” NCT07708025 ↗ “Oral iron supplementation with ferrous sulfate has been considered the standard of care” NCT03957057 ↗ “Ca. 200-300 mg of ferrous sulfate will be administered orally every day for 3 months.” NCT05060731 ↗ “Group II received ferrous sulfate (element Fe 1-2 mg/kg•day) once a day for 6 months” NCT01355263 ↗ “Participants given tablet Ferrous sulfate, 325 mg orally three times a day.” NCT07340450 ↗ “40 doses of 30 mg of ferrous sulfate during a 10-month intervention period” NCT00992823 ↗ “Oral ferrous sulfate 325 mg twice daily was administered for 12 months.” PMID 36406817 ↗ Nov 2022 Show 81 more sources
Known as	Dried Ferrous Sulfate	ClinicalTrials.gov intervention name — accepted as the source's own label NCT05299411 ↗
Known as	Eisen-II-Sulfat	“Oral iron supplementation with Eisen-II-Sulfat (Tardyferon ®) Every second day 2 x 80 mg Tardyferon® for a duration of 12 weeks.” NCT06238895 ↗
Known as	FeFum	“a complementary food (CF) fortified with sodium iron EDTA (NaFeEDTA) plus either ferrous fumarate (FeFum) or ferric pyrophosphate (FePP)” PMID 28708072 ↗ Jul 2017
Known as	Fer-In-Sol	ClinicalTrials.gov intervention name — accepted as the source's own label NCT02905981 ↗ 1 NCT02767128 ↗
Known as	Ferli-6	“3 ferrous fumarate tablets (Ferli-6®) everyday” NCT00746551 ↗
Known as	Feroba-YOU	“Ferrous sulfate(Feroba-YOU) per oral” NCT03229954 ↗
Known as	Ferro Gradumet	“either hydroxide polymaltose \[Ferrum Haussman®\] or ferrous sulfate \[Ferro Gradumet®\]” NCT07708025 ↗
Known as	FerroGrad	“Drug: FerroGrad by Abbott Dosage: one capsule three times /day containing150 mg of dried ferrous sulfate capsules (Ferrofol capsules, Eipico, Egypt), with placebo sachets.” NCT03202615 ↗
Known as	Ferrous fumarate	“LNG/ethinyl estradiol (EE)/ferrous fumarate combined oral contraceptive (COC) regimen” NCT05233956 ↗ 32 “patients are randomized to 300 mg of ferrous fumarate or placebo for 4 weeks” NCT00152841 ↗ “Calcium Carbonate 150 mg/day Ferrous Fumarate 27 mg/day Zinc Oxide 25 mg/day” NCT02620345 ↗ “3 ferrous fumarate tablets (Ferli-6®) everyday” NCT00746551 ↗ “ferrous fumarate or ferrous gluconate” NCT01414075 ↗ “Ferrous fumarate” NCT01155375 ↗ NCT05581420 ↗ NCT01634945 ↗ NCT00136266 ↗ NCT07014371 ↗ NCT06321887 ↗ Show 22 more sources
Known as	ferrous succinate	“Other drugs to treat anemia include: Recombinant human eythropoietin (RH-EPO), iron agents (ferrous succinate, polysaccharide iron complex, iron sucrose, etc.)” NCT05691257 ↗ 7 “If necessary, oral ferrous succinate, vitamins B12 and folic acid will be administered.” NCT03010579 ↗ “ferrous succinate” NCT04975074 ↗ NCT03891277 ↗ NCT05784870 ↗ NCT05714007 ↗ NCT06830941 ↗ NCT02631668 ↗
Known as	ferrous sulphate	“Directly Observed Home based Daily Iron( ferrous sulphate) therapy (DOHBIT) will be provided to the anemic women by the local village volunteers.” NCT01129843 ↗ 31 “200 mg of dried ferrous sulphate tablet once daily for 30 days on empty stomach but may be taken with meals to avoid stomach upset” NCT03759353 ↗ “after single oral administration of 2 tablets of L0008 80 mg (as ferrous sulphate) in women with iron deficiency anaemia.” NCT01757119 ↗ “The pregnant women randomized to the control arm (FS) will be given one 200mg tablet of ferrous sulphate” NCT04976179 ↗ “oral ferrous sulphate 325 mg thrice daily for a total of 195 mg elemental iron daily for 56 days” PMID 20929915 ↗ Oct 2010 “Routine group: 60 mg per day of ferrous sulphate (combination with folic acid) daily.” NCT00488579 ↗ “either oral Ferrous Sulphate (FS) 200 mg three times a day or placebo” PMID 36578916 ↗ Nov 2022 “ferrous sulphate oral in the form of syrup” NCT06176430 ↗ “oral iron(ferrous Sulphate)” NCT07110935 ↗ NCT01701310 ↗ NCT01628770 ↗ Show 21 more sources
Known as	Ferrous sulphate tablets	“Drug: Ferrous sulphate tablets” NCT00919230 ↗
Known as	FeSO(4)	“ferrous sulfate (FeSO(4)) 325 mg orally thrice daily for 6 weeks.” PMID 17666600 ↗ Aug 2007
Known as	Hema-caps	“75 pregnant women will recommended to take ferrous fumarate e.g. Hema-caps (ferrous fumarate 350 mg with elemental iron 115mg) prepared by another egyptian pharmaceutical...” NCT03830034 ↗
Known as	Iron	“Iron (ferrous sulfate)” NCT00459225 ↗
Known as	L0008	“after single oral administration of 2 tablets of L0008 80 mg (as ferrous sulphate)” NCT01757119 ↗
Known as	Oral Iron	“Oral Iron (Ferrous sulphate)” NCT07659184 ↗
Known as	Tardyfer	“ferrous sulphate (Tardyfer®) 160 mg daily for 6 weeks” NCT03957057 ↗
Known as	Tardyferon	“Oral iron supplementation with Eisen-II-Sulfat (Tardyferon ®) Every second day 2 x 80 mg Tardyferon® for a duration of 12 weeks.” NCT06238895 ↗
Known as	Upsher-Smith ferrous sulfate 325 mg tablets NDC# 00245-0108-11	“Upsher-Smith ferrous sulfate 325 mg tablets NDC# 00245-0108-11” NCT01438372 ↗
Modality	Diagnostic / imaging agent	“For assessment of incorporation of iron into erythrocytes, participants will be administered ferrous sulfate containing a stable isotope of iron (57Fe) orally” NCT03457701 ↗
Route	Oral	“Oral Iron” NCT00223938 ↗