drugset / Trial / NCT00002638

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Relapsed Acute Lymphocytic Leukemia

NCT00002638

Phase 2 Completed 30 enrolled University of Nebraska
Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by peripheral stem cell transplantation in treating children who have relapsed acute lymphocytic leukemia.

Timeline

Start
1995-03
Primary completion
Completion
2005-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified Intravenous
Subject Cytarabine Small molecule Intravenous
Subject Etoposide Small molecule Intravenous
Subject carmustine Small molecule Intravenous
Background filgrastim Protein / enzyme biologic
Background sargramostim Protein / enzyme biologic

Indications