drugset / Trial / NCT00244517

DIAFAX I+II-Effects of Inhalative Anesthetics on Left Ventricular Diastolic Function

NCT00244517

Phase 4 Terminated 60 enrolled University Hospital, Basel, Switzerland
RandomizedParallel-groupTriple-blindDiagnostic

Summary

Anaesthetics may impair the diastolic function of the heart, but the importance of this finding for patients has not been sufficiently examined. Specially the effects on diastolic function in patients with diastolic dysfunction has to be determined. The aim of this study is to examine the effect of isoflurane (only part I), sevoflurane and desflurane (part I+II) on the diastolic left ventricular function by doppler echocardiography.

Timeline

Start
2004-06
Primary completion
2010-04
Completion
2010-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Desflurane Other / unclassified 1 unknown
Comparator Isoflurane Other / unclassified 1 unknown
Comparator Sevoflurane Other / unclassified 1 unknown
Comparator Remifentanil Small molecule 2 ng/ml