drugset / Trial / NCT01358253

Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia

NCT01358253

Phase 4 Completed 100 enrolled Ruijin Hospital
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The main purpose of this study is to evaluate the safety and efficacy of Rituximab combined with chemotherapy in CD20+ adult acute lymphoblastic leukemia.

Timeline

Start
2010-12
Primary completion
2012-12
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Rituximab Monoclonal antibody 375 mg/m2 Intravenous
Background Cyclophosphamide Other / unclassified 300 mg/m2 Intravenous
Background Cytarabine Small molecule 2 g Intravenous
Background Dexamethasone Small molecule 40 mg Intravenous
Background Doxorubicin Other / unclassified 50 mg/m2 Intravenous
Background MERCAPTOPURINE ANHYDROUS Small molecule 60 mg/m2
Background Methotrexate Small molecule 25 mg/m2 Intravenous
Background Prednisone Other / unclassified 40 mg/m2
Background Vincristine Small molecule 1.4 mg/m2 Intravenous
Background asparaginase Protein / enzyme biologic 6000 unknown Intravenous