The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy

Completed 67 enrolled Yonsei University

RandomizedParallel-groupDouble-blindSupportive care

Summary

Intraocular pressure is significantly increase during robot-assisted laparoscopic radical prostatectomy which is performed in a steep trendelenburg position at prolonged times of pneumoperitoneum. Therefore investigators decided to evaluate the impacts of surgical visibility through deep neuromuscular blockade on intraocular pressure in patients undergoing Robot-Assisted Laparoscopic Radical Prostatectomy.

Timeline

Start: 2014-05
Primary completion: 2014-12
Completion: 2014-12

Publications

Yoo YC, Kim NY, Shin S, Choi YD, Hong JH, Kim CY, Park H, Bai SJ. The Intraocular Pressure under Deep versus Moderate Neuromuscular Blockade during Low-Pressure Robot Assisted Laparoscopic Radical Prostatectomy in a Randomized Trial. PLoS One. 2015 Aug 28;10(8):e0135412. doi: 10.1371/journal.pone.0135412. eCollection 2015.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Atracurium	Small molecule	—	—
Comparator	Neostigmine	Other / unclassified	—	—
Subject	Rocuronium	Other / unclassified	—	—
Subject	Sugammadex	Other / unclassified	—	—

Indications

No indication recorded.