drugset / Trial / NCT02292082

The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)

NCT02292082

Phase 4 Completed 111 enrolled Hospital for Special Surgery, New York
RandomizedParallel-groupDouble-blindTreatment

Summary

Total knee replacement is associated with severe post-operative pain. The purpose of this study is to compare two methods of treatment for pain control following Total Knee Replacement with an accelerated physical therapy protocol to aid the achievement of rehab milestones.

Timeline

Start
2014-11
Primary completion
2016-08
Completion
2016-08

Drugs

EvaluationDrugModalityDoseRoute
Background Bupivacaine Other / unclassified 0.25 %
Background Bupivacaine Other / unclassified 0.5 %
Background Cefazolin Small molecule 500 mg
Background Dexamethasone Small molecule 2 mg
Background Methylprednisolone Other / unclassified 40 mg/ml
Background Midazolam Small molecule Intravenous
Background Morphine Other / unclassified 8 mg/ml
Background Propofol Small molecule Intravenous

Indications