drugset / Trial / NCT02727712

Studies of Application of Combined General Anesthesia and Bilateral TPVB in OPCABG

NCT02727712

Phase 4 Unknown 60 enrolled Xiangya Hospital of Central South University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study intends to compare the combination of general anesthesia (GA) and single-shot bilateral thoracic paravertebral block (TPVB) by ropivacaine in the patients undergoing off-pump coronary artery bypass surgery ( OPCAB) with traditional general anesthesia (GA) perioperative management of patients, committed to reducing patient's physical and psychological stress by surgical trauma, achieve the purpose of fast recovery, in order to establish an more effective perioperative management during off-pump coronary artery bypass surgery, improve patients' satisfaction and to accelerate postoperative rehabilitation safely.

Timeline

Start
2016-04
Primary completion
2016-09
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Background Dexmedetomidine Other / unclassified 0.5 ug/kg
Background Dexmedetomidine Other / unclassified 1 ug/kg
Background Etomidate Small molecule 0.2 mg/kg
Background Etomidate Small molecule 0.6 mg/kg
Background Hydromorphone Other / unclassified 0.15 mg/kg Intravenous
Background Sevoflurane Other / unclassified
Background Sufentanil Other / unclassified 0.01 ug/kg
Background Sufentanil Other / unclassified 0.04 ug/kg
Background Vecuronium Small molecule 0.06 mg/kg
Background Vecuronium Small molecule 0.12 mg/kg