drugset / Trial / NCT03417193
Opioid Free Anesthesia and Major Spine Surgery
RandomizedParallel-groupTriple-blindTreatment
Summary
This study compares the intraoperative opioid free anesthesia approach in multilevel spine posterior instrumentation surgery to a conventional opioid-based anesthesia. Half of participants will receive opioid free anesthesia with dexmedetomidine, lidocaine and ketamine while the other half will receive opioid based anesthesia with fentanyl, remi-fentanyl and ketamine
Timeline
- Start
- 2018-01-29
- Primary completion
- 2023-02-16
- Completion
- 2023-02-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | — | Intravenous |
| Comparator | Fentanyl | Other / unclassified | — | — |
| Comparator | Lidocaine | Other / unclassified | — | Intravenous |
| Comparator | Remifentanil | Small molecule | — | — |