drugset / Trial / NCT03475121

Treatment Protocol for Non-Metastatic Unilateral Retinoblastoma

NCT03475121

Phase 3 Completed 84 enrolled Hospital JP Garrahan
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This protocol provides guidelines for the management of non-metastatic unilateral retinoblastoma and introduces an innovative adjuvant therapy for higher risk patients based upon the results of the Grupo de America Latina de Oncologia Pediatrica (GALOP) I study. Conservative therapy will be not protocolized.

Timeline

Start
2018-01-01
Primary completion
2023-01-31
Completion
2025-03-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule
Subject Cyclophosphamide Other / unclassified
Subject Etoposide Small molecule
Subject Idarubicin Small molecule
Subject Topotecan Small molecule Intrathecal
Subject Vincristine Small molecule