drugset / Trial / NCT03726268
Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)
RandomizedParallel-groupDouble-blindTreatment
Summary
The overall goal of this research is to improve perioperative pain treatment, decrease post-operative opioid consumption, diminish opioid related side effects, and reduce postop opioid prescribing (and hence opportunity for diversion, abuse, addiction, and fatal overdose).
Timeline
- Start
- 2018-11-29
- Primary completion
- 2023-07-30
- Completion
- 2024-01-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | — | Intravenous |
| Comparator | Hydromorphone | Other / unclassified | — | Intravenous |
| Comparator | Methadone | Other / unclassified | 0.15 mg/kg | Intravenous |
| Comparator | Methadone | Other / unclassified | 0.3 mg/kg | Intravenous |
| Comparator | Methadone | Other / unclassified | 10 mg | Intravenous |
| Comparator | Methadone | Other / unclassified | 15 mg | Intravenous |
| Comparator | Morphine | Other / unclassified | — | Intravenous |
| Comparator | Sufentanil | Other / unclassified | — | Intravenous |