drugset
drugset / Trial / NCT04025606

Paravertebral Block Versus Thoracic Epidural Analgesia

NCT04025606 ↗

Completed 94 enrolled St. Olavs Hospital
RandomizedParallel-groupSingle-blindTreatment

Summary

Thoracic epidural analgesia (TEA) is the basic method of analgesia in patients undergoing pulmonary lobectomy. TEA is considered to be a safe and thoroughly investigated method of pain relief that rarely causes serious complications. However, blocking the nerves as they emerge from the spinal column (paravertebral block, PVB) may represent an alternative method with some potential benefits. In this study, TEA and PVB will be compared for patients undergoing pulmonary lobectomy by video assisted thoracoscopic surgery. The aim of the study is to test the hypothesis, that PVB is a time-saving procedure compared with TEA on the day of surgery and that PVB is as efficient in postoperative pain reduction as TEA.

Timeline

Start
2019-06-24
Primary completion
2022-12-01
Completion
2022-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 2 mg/ml Other
Subject Bupivacaine Other / unclassified 2.5 mg/ml Other
Subject Bupivacaine Other / unclassified 5 mg/ml Other
Background Acetaminophen Small molecule — Oral
Background Epinephrine Other / unclassified 2 ug/ml Other
Background Fentanyl Other / unclassified 2 ug/ml Other
Background Oxycodone Other / unclassified — Oral

Indications

lung cancer