drugset / Trial / NCT04095754

Can Head Position Improve Surgical Field During Ear Surgery?

NCT04095754

Completed 225 enrolled Ain Shams University
RandomizedParallel-groupTriple-blindSupportive care

Summary

Middle ear surgeries utilizes microscope in a narrow field. They are better performed under controlled hypotension, to minimize bleeding and improve surgical field visualization and hence improve results.Head-up or anti-trendelenburg position influences intraoperative bleeding by generating regional ischaemia in sites elevated above the level of the heart. Also by augmenting the effect of vasodilators through pooling of blood in dilated veins.

Timeline

Start
2020-04-12
Primary completion
2020-10-14
Completion
2020-10-14

Drugs

EvaluationDrugModalityDoseRoute
Background Atracurium Small molecule 0.1 mg/kg
Background Dexmedetomidine Other / unclassified 0.4 ug/kg
Background Fentanyl Other / unclassified 1 ug/kg
Background Isoflurane Other / unclassified 1 %
Background Propofol Small molecule 1.5 mg/kg
Background Propofol Small molecule 2 mg/kg

Indications

No indication recorded.