drugset / Trial / NCT04260659
Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy
RandomizedParallel-groupTriple-blindTreatment
Summary
Opioid free anesthesia is an anesthetic technique, in which administration of multimodal analgesia and sympathicolytics provides hemodynamic stability without use of opioids. Such management may be beneficial to the obese patients undergoing laparoscopic sleeve gastrectomy. Our study aims to compare opioid free anesthesia in such patients with standard, short-acting opioid based.
Timeline
- Start
- 2020-02-04
- Primary completion
- 2022-10-06
- Completion
- 2023-02-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Intravenous |
| Subject | Ketamine | Small molecule | 0.5 mg/kg | Intravenous |
| Subject | Lidocaine | Other / unclassified | 3 mg/kg | Intravenous |
| Subject | Magnesium Sulfate | Other / unclassified | 50 mg/kg | Intravenous |
| Comparator | Remifentanil | Small molecule | 6 ng/ml | — |
| Background | Fentanyl | Other / unclassified | 100 ug | Intravenous |