drugset / Trial / NCT04603911

RCT Comparing ESPB Solutions in Breast Surgery

NCT04603911

Phase 2 Completed 75 enrolled Tufts Medical Center
RandomizedParallel-groupTriple-blindOther

Summary

The object of our research is to investigate the relative efficacy of liposomal bupivacaine administered via an Erector Spinae Plane (ESP) block as compared to our standard of care medication solution of (bupivacaine mixed with epinephrine, dexamethasone, and clonidine) for pain management in subjects undergoing bilateral surgical intervention for breast cancer. This will be an investigator-initiated, double-blind, patient-controlled, randomized control trial comparing pain scores at 48 hours after injection.

Timeline

Start
2020-12-04
Primary completion
2023-04-10
Completion
2023-04-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified Other
Comparator Clonidine Other / unclassified Other
Comparator Dexamethasone Small molecule Other
Comparator Epinephrine Other / unclassified Other

Indications