drugset / Trial / NCT05676814

Pecto-intercostal Fascial Block (PIFB) for Postop Analgesia Following Sternotomy in Cardiac Surgery Patients

NCT05676814

Phase 4 Completed 31 enrolled Wake Forest University Health Sciences
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this randomized, triple-blinded, prospective, feasibility study is to compare postoperative analgesia provided by Pecto-intercostal Fascial Block (PIFB) when performed with local anesthetic solution with or without perineural adjuvants in patients following cardiac surgery involving sternotomy. The study team hypothesizes that the patients receiving PIFB with bupivacaine with epinephrine, clonidine, and dexamethasone will have lower dynamic pain over the first 36 hours compared to those receiving PIFB with just bupivacaine and epinephrine.

Timeline

Start
2023-03-24
Primary completion
2023-06-23
Completion
2023-06-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Clonidine Other / unclassified
Subject Dexamethasone Small molecule
Comparator Bupivacaine Other / unclassified
Comparator Epinephrine Other / unclassified

Indications

No indication recorded.