drugset / Trial / NCT06418308
Intrathecal Dexmedetomidine vs Epinephrine
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-inferior to adjunctive intrathecal epinephrine in providing better single-dose spinal analgesia during cesarean section.
Timeline
- Start
- 2024-09-17
- Primary completion
- 2026-05-20
- Completion
- 2026-05-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 5 ug | Intrathecal |
| Comparator | Epinephrine | Other / unclassified | 200 ug | Intrathecal |
| Comparator | Bupivacaine | Other / unclassified | 10.25 mg | Intrathecal |
| Comparator | Morphine | Other / unclassified | 0.125 mg | Intrathecal |
Indications
No indication recorded.