drugset / Trial / NCT06418308

Intrathecal Dexmedetomidine vs Epinephrine

NCT06418308 ↗

Phase 4 Completed 90 enrolled Icahn School of Medicine at Mount Sinai
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-inferior to adjunctive intrathecal epinephrine in providing better single-dose spinal analgesia during cesarean section.

Timeline

Start
2024-09-17
Primary completion
2026-05-20
Completion
2026-05-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 5 ug Intrathecal
Comparator Epinephrine Other / unclassified 200 ug Intrathecal
Comparator Bupivacaine Other / unclassified 10.25 mg Intrathecal
Comparator Morphine Other / unclassified 0.125 mg Intrathecal

Indications

No indication recorded.