drugset / Trial / NCT03408340

Paravertebral Nerve Blocks in Neonates

NCT03408340

Phase 4 Terminated 16 enrolled Emory University
RandomizedParallel-groupOpen-labelSupportive care

Summary

This study is a prospective, randomized, non-blinded clinical trial examining the use of paravertebral peripheral nerve block in the neonatal and infant populations. The primary aim of this study is to determine the feasibility of studying whether a single-shot paravertebral nerve block is effective in providing intraoperative and postoperative pain control in infants undergoing a thoracotomy for coarctation of the aorta. This will be determined by comparing consumption of narcotics, expressed as morphine equivalents, in the standard of care and intervention groups.

Timeline

Start
2018-07-18
Primary completion
2020-07-28
Completion
2020-07-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified
Comparator Epinephrine Other / unclassified
Comparator Fentanyl Other / unclassified 1 ug/kg Intravenous
Comparator Ketamine Small molecule 2 mg/kg
Comparator Propofol Small molecule 3 mg/kg
Comparator Rocuronium Other / unclassified 1.2 mg/kg
Comparator Sevoflurane Other / unclassified