drugset / Trial / NCT03408340
Paravertebral Nerve Blocks in Neonates
RandomizedParallel-groupOpen-labelSupportive care
Summary
This study is a prospective, randomized, non-blinded clinical trial examining the use of paravertebral peripheral nerve block in the neonatal and infant populations. The primary aim of this study is to determine the feasibility of studying whether a single-shot paravertebral nerve block is effective in providing intraoperative and postoperative pain control in infants undergoing a thoracotomy for coarctation of the aorta. This will be determined by comparing consumption of narcotics, expressed as morphine equivalents, in the standard of care and intervention groups.
Timeline
- Start
- 2018-07-18
- Primary completion
- 2020-07-28
- Completion
- 2020-07-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | — | — |
| Comparator | Epinephrine | Other / unclassified | — | — |
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | Intravenous |
| Comparator | Ketamine | Small molecule | 2 mg/kg | — |
| Comparator | Propofol | Small molecule | 3 mg/kg | — |
| Comparator | Rocuronium | Other / unclassified | 1.2 mg/kg | — |
| Comparator | Sevoflurane | Other / unclassified | — | — |