General Anesthesia With or Without Local Ear Block in Middle Ear Surgeries
Summary
Background: Proper selection of anesthetic technique is important in middle ear microsurgery. Controlled hypotension in ear surgery decreases blood loss with improved quality of the surgical field, however, it is associated with resistance to vasodilators and delayed recovery from anesthesia. The use of local anesthetic technique alone in middle ear surgery decreases bleeding and reduces postoperative pain, however, pain on injection, noise, and head-neck position had been reported with the increased risk of patient injuries. This study aimed to compare the effects of local ear block combined with general anesthesia versus general anesthesia alone, regarding intraoperative hemodynamics, anesthetic consumption, recovery characteristics, postoperative pain, adverse effects and postoperative complications.
Timeline
- Start
- 2018-07-06
- Primary completion
- 2018-12-01
- Completion
- 2018-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 0.25 % | — |
| Comparator | Atracurium | Small molecule | 0.5 mg/kg | — |
| Comparator | Fentanyl | Other / unclassified | 2 ug/kg | — |
| Comparator | Isoflurane | Other / unclassified | — | — |
| Comparator | Lidocaine | Other / unclassified | 0.5 mg/kg | — |
| Comparator | Midazolam | Small molecule | 0.02 mg/kg | — |
| Comparator | Propofol | Small molecule | 2 mg/kg | — |
| Comparator | Propofol | Small molecule | 3 mg/kg | — |
| Comparator | Propranolol | Small molecule | 0.2 mg | — |
| Comparator | nitroglycerine | Unknown | 0.5 ug/kg | — |
| Comparator | nitroglycerine | Unknown | 10 ug/kg | — |
Indications
No indication recorded.