drugset / Trial / NCT04365686
Smooth Extubation With Ketofol for Induction of General Anesthesia in Laparoscopic Drilling of Polycystic Ovary
RandomizedParallel-groupDouble-blindPrevention
Summary
the effect of ketofol, a combination of propofol and ketamine, on hemodynamics and airway response during induction of general anesthesia has been studied before. Its effect on the smoothness of extubation has not been studied before. In the present study; we aimed to assess the effect of ketofol on the smoothness of extubation as regards, airway response, sedation score during suction and extubation and hemodynamic changes comparing it with propofol for induction of general anesthesia.
Timeline
- Start
- 2019-04-01
- Primary completion
- 2020-04-12
- Completion
- 2020-04-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketamine | Small molecule | 0.5 mg/kg | — |
| Comparator | Propofol | Small molecule | 1 mg/kg | — |
| Comparator | Propofol | Small molecule | 2 mg/kg | — |
| Background | Atracurium | Small molecule | 0.1 mg/kg | — |
| Background | Atracurium | Small molecule | 0.5 mg/kg | — |
| Background | Atropine | Other / unclassified | 0.01 mg/kg | — |
| Background | Fentanyl | Other / unclassified | 2 ug/kg | — |
| Background | Isoflurane | Other / unclassified | 1.5 % | — |
| Background | Midazolam | Small molecule | 2 mg | — |
| Background | Neostigmine | Other / unclassified | 0.05 mg | — |
| Background | Ondansetron | Other / unclassified | 4 mg | — |
Indications
No indication recorded.