drugset / Trial / NCT00003815

Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma

NCT00003815

RandomizedTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Bone marrow transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to study the effectiveness of chemotherapy and radiation therapy plus bone marrow transplantation in treating patients who have aggressive non-Hodgkin's lymphoma.

Timeline

Start
1994-06
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Bleomycin Unknown Intravenous
Subject Cyclophosphamide Other / unclassified
Subject Cytarabine Small molecule Intravenous
Subject Doxorubicin Other / unclassified Intravenous
Subject Etoposide Small molecule Oral
Subject Melphalan Small molecule Intravenous
Subject Prednisolone Other / unclassified Oral
Subject Vincristine Small molecule
Subject carmustine Small molecule Intravenous

Indications