drugset / Trial / NCT01703910
Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic
Phase 2
Completed
29 enrolled
Spanish National Cancer Research Centre
Apices Soluciones S.L. · collabGrupo Hospital de Madrid · collabHospital Universitario de Fuenlabrada · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the feasibility of selecting personalized therapies for colon cancer patients who have failed standard treatments, using a new methodology based on the determination of a profile of chemosensitivity by comprehensive genetic expression analysis from tumor samples.
Timeline
- Start
- 2012-11
- Primary completion
- 2012-11
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Capecitabine | Small molecule | — | — |
| Comparator | Cetuximab | Monoclonal antibody | — | — |
| Comparator | Cisplatin | Other / unclassified | — | — |
| Comparator | Docetaxel | Small molecule | — | — |
| Comparator | Doxorubicin | Other / unclassified | — | — |
| Comparator | Erlotinib | Small molecule | — | — |
| Comparator | Etoposide | Small molecule | — | — |
| Comparator | Gemcitabine | Small molecule | — | — |
| Comparator | Irinotecan | Small molecule | — | — |
| Comparator | Mitomycin C | Other / unclassified | — | — |
| Comparator | Oxaliplatin | Small molecule | — | — |
| Comparator | Paclitaxel | Small molecule | — | — |
| Comparator | Pemetrexed | Small molecule | — | — |
| Comparator | Raltitrexed | Small molecule | — | — |
| Comparator | Sorafenib | Small molecule | — | — |
| Comparator | Topotecan | Small molecule | — | — |
| Comparator | Vinorelbine | Small molecule | — | — |
| Comparator | dasatinib anhydrous | Small molecule | — | — |
| Comparator | fluorouracil | Small molecule | — | — |