drugset / Trial / NCT03422354

Effect of Ultrasound Guided L1,L2 Paravertebral Block in Decrease the Requirements for Hypotensive Drugs During General Anesthesia in Patients Undergoing Hip Surgeries.

NCT03422354

RandomizedParallel-groupDouble-blindSupportive care

Summary

The paravertebral block (PVB) is a block of the mixed nerve soon after it exits the intervertebral foramen.(2) It provides intense unilateral analgesia of long duration and has become the primary anesthetic for many applications.(3) Paravertebral Block (PVB) involves injection of local anaesthetic in a space immediately lateral to where the spinal nerves emerge from the intervertebral foramina. This technique is being used increasingly for not only intra-operative and post-operative analgesia but also as a sole anaesthetic technique for carrying out various procedures. This popularity is mainly due to the ease of the technique and fewer complications.(4) The increasing demand for hip arthroplasties over the last decades has sparked the creation of new and innovative anesthetic techniques and analgesic pathways with the goal to support best possible outcomes among this frequently elderly patient population. As a result, today different perioperative treatment pathways are available to physicians and their patients. In this context, the focus has shifted to techniques based on regional anesthetic and analgesic techniques. This trajectory has been fueled by a number of advantages including effective, long-lasting and focused pain control, decreased need for systemic analgesics and earlier mobilization.

Timeline

Start
2018-02-12
Primary completion
2018-05-10
Completion
2018-05-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule 1 g Intravenous
Comparator Atracurium Small molecule 0.5 unknown
Comparator Bupivacaine Other / unclassified 0.25 % Other
Comparator Fentanyl Other / unclassified 100 ug
Comparator Lidocaine Other / unclassified 1 % Other
Comparator Meperidine Unknown 50 mg Intravenous
Comparator Propofol Small molecule 2 mg/kg
Comparator Propranolol Small molecule
Comparator nitroglycerine Unknown

Indications

No indication recorded.