drugset / Trial / NCT01858090
Intrathecal Levobupivacaine With Opioids for Caesarean Section
RandomizedParallel-groupDouble-blindTreatment
Summary
In this prospective, randomized, double-blind, controlled study, the aim was to compare the effect of adding fentanyl (10 µg) or sufentanil (2.5 µg) to levobupivacaine (2.2±0.2 ml 0.5%) on the intraoperative anesthesia quality, block characteristics, the side effects on the newborn and mother, the duration of postoperative analgesia, and surgeon satisfaction score.
Timeline
- Start
- 2009-01
- Primary completion
- 2009-10
- Completion
- 2010-01
Publications
- Background Karaman S, Kocabas S, Uyar M, Hayzaran S, Firat V. The effects of sufentanil or morphine added to hyperbaric bupivacaine in spinal anaesthesia for caesarean section. Eur J Anaesthesiol. 2006 Apr;23(4):285-91. doi: 10.1017/S0265021505001869. Epub 2006 Jan 27.
- Bozdogan Ozyilkan N, Kocum A, Sener M, Caliskan E, Tarim E, Ergenoglu P, Aribogan A. Comparison of intrathecal levobupivacaine combined with sufentanil, fentanyl, or placebo for elective caesarean section: a prospective, randomized, double-blind, controlled study. Curr Ther Res Clin Exp. 2013 Dec;75:64-70. doi: 10.1016/j.curtheres.2013.09.003.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | 10 ug | Intrathecal |
| Comparator | Levobupivacaine | Other / unclassified | 11 mg | Intrathecal |
| Comparator | Levobupivacaine | Other / unclassified | 12 mg | Intrathecal |
| Comparator | Sufentanil | Other / unclassified | 2.5 ug | Intrathecal |
| Comparator | Atropine | Other / unclassified | 0.5 mg | — |
| Comparator | Diclofenac | Other / unclassified | 75 mg | Intramuscular |
| Comparator | Diphenhydramine | Unknown | 25 mg | — |
| Comparator | Ephedrine | Small molecule | 5 mg | — |
| Comparator | Meperidine | Unknown | 50 mg | Intramuscular |
| Comparator | Metoclopramide | Small molecule | 10 mg | Intravenous |
| Comparator | Propofol | Small molecule | 0.5 mg/kg | Intravenous |
Indications
No indication recorded.