drugset / Trial / NCT05582499
Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to establish a prospective, single-center platform research based on clinical subtypes to explore precision neoadjuvant therapy in patients with operable breast cancer who met the indications for neoadjuvant chemotherapy and by the update of basic translational research in the center, especially the refinement of typing, the discovery of new targets and the development of novel targeted drugs, verified the effectiveness of new targeted drugs in neoadjuvant therapy.
Timeline
- Start
- 2022-11-01
- Primary completion
- 2027-12-31
- Completion
- 2029-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 9MW2821 | Monoclonal antibody | — | — |
| Subject | Adebrelimab | Monoclonal antibody | — | — |
| Subject | Benmelstobart | Monoclonal antibody | — | — |
| Subject | Camrelizumab | Monoclonal antibody | — | — |
| Subject | Carboplatin | Small molecule | — | — |
| Subject | Catequentinib | Small molecule | — | — |
| Subject | Cyclophosphamide | Other / unclassified | — | — |
| Subject | Dalpiciclib | Small molecule | — | — |
| Subject | Epirubicin | Small molecule | — | — |
| Subject | Famitinib | Small molecule | — | — |
| Subject | Fluzoparib | Small molecule | — | — |
| Subject | Goserelin | Other / unclassified | — | — |
| Subject | HB1801 | Unknown | — | — |
| Subject | HRS-4508 | Unknown | — | — |
| Subject | HRS-6209 | Small molecule | — | — |
| Subject | IBI354 | Monoclonal antibody | — | — |
| Subject | Ivonescimab | Monoclonal antibody | — | — |
| Subject | JS207 | Monoclonal antibody | — | — |
| Subject | JSKN003 | Monoclonal antibody | — | — |
| Subject | LEM | Unknown | — | — |
| Subject | Letrozole | Other / unclassified | — | — |
| Subject | Nab-paclitaxel | Small molecule | — | — |
| Subject | Paclitaxel | Small molecule | — | — |
| Subject | Pertuzumab | Monoclonal antibody | — | — |
| Subject | Pyrotinib | Small molecule | — | — |
| Subject | Rivoceranib | Small molecule | — | — |
| Subject | SHR-4602 | Monoclonal antibody | — | — |
| Subject | SHR-A1811 | Monoclonal antibody | — | — |
| Subject | SHR-A1921 | Monoclonal antibody | — | — |
| Subject | TQB2102 | Monoclonal antibody | — | — |
| Subject | TQB2868 | Protein / enzyme biologic | — | — |
| Subject | Trastuzumab | Monoclonal antibody | — | — |