drugset / Trial / NCT07558226
Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy
RandomizedParallel-groupTriple-blindSupportive care
Summary
It is a prospective, randomized, controlled and superiority clinical trial, with the objective of comparing the effectiveness of multimodal anesthesia versus conventional anesthesia in patients undergoing oncological robotic nephrectomy within a short-stay surgery program (SSA). The effect of no specific drug will be evaluated, but rather the anesthetic approach ologies of surgical patients. The clinical trial will be carried out in a third-level university hospital, between the first half of 2026 and the second half of 2027 and, after approval by the corresponding Clinical Research Ethics Committee.
Timeline
- Start
- 2026-05-02
- Primary completion
- 2027-11-30
- Completion
- 2027-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 1 g | Intravenous |
| Comparator | Adolonta | Unknown | — | — |
| Comparator | Bupivacaine | Other / unclassified | 0.25 % | Other |
| Comparator | Bupivacaine | Other / unclassified | 2 ml | Other |
| Comparator | Bupivacaine | Other / unclassified | 10 ml | Other |
| Comparator | Dexamethasone | Small molecule | 4 mg | Intravenous |
| Comparator | Dexamethasone | Small molecule | 8 mg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | Intravenous |
| Comparator | Ketamine | Small molecule | 0.1 mg/kg | — |
| Comparator | Ketamine | Small molecule | 0.2 mg/kg | — |
| Comparator | Ketamine | Small molecule | 0.25 mg/kg | — |
| Comparator | Ketamine | Small molecule | 0.5 mg/kg | — |
| Comparator | Lidocaine | Other / unclassified | 1 mg/kg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 1.5 mg/kg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 2 mg/kg | Intravenous |
| Comparator | Magnesi Sulfate | Unknown | 30 mg/kg | Intravenous |
| Comparator | Magnesi Sulfate | Unknown | 50 mg/kg | Intravenous |
| Comparator | Metamizole | Unknown | 1 g | Intravenous |
| Comparator | Methadone | Other / unclassified | 0.1 mg/kg | Intravenous |
| Comparator | Methadone | Other / unclassified | 0.5 mg/kg | Intravenous |
| Comparator | Methadone | Other / unclassified | 1 mg/kg | Intravenous |
| Comparator | Methadone | Other / unclassified | 1.5 mg/kg | Intravenous |
| Comparator | Midazolam | Small molecule | 1 mg | — |
| Comparator | Midazolam | Small molecule | 2 mg | — |
| Comparator | Morphine | Other / unclassified | — | — |
| Comparator | Ondansetron | Other / unclassified | 4 mg | Intravenous |
| Comparator | Ondansetron | Other / unclassified | 8 mg | Intravenous |
| Comparator | Propofol | Small molecule | 1 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 2 mg/kg | Intravenous |
| Comparator | Remifentanil | Small molecule | 0.05 ug/kg | — |
| Comparator | Remifentanil | Small molecule | 0.2 ug/kg | — |
| Comparator | Rocuroni | Unknown | 0.3 mg/kg | Intravenous |
| Comparator | Scopolamine | Unknown | — | Intravenous |
| Comparator | Sevoflurane | Other / unclassified | — | — |
Indications
No indication recorded.