drugset / Trial / NCT04766996
PROUD Study - Preventing Opioid Use Disorders
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The objective of this study is to pilot an opioid free anesthetic protocol for patients undergoing total hip replacement.
Timeline
- Start
- 2021-05-17
- Primary completion
- 2021-12-27
- Completion
- 2021-12-27
Outcome
Outcome not reported
Stopped: “Loss of surgery team member deemed the study procedures impossible to achieve, and no replacement could be found in a timely manner to complete trial as initially planned.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Acetaminophen | Small molecule | 1000 mg | — |
| Background | Aspirin | Small molecule | 81 mg | — |
| Background | Bupivacaine | Other / unclassified | 0.5 % | — |
| Background | Cefazolin | Small molecule | 2 g | — |
| Background | Cefazolin | Small molecule | 3 g | — |
| Background | Dexamethasone | Small molecule | 10 mg | — |
| Background | Diclofenac | Other / unclassified | 1 % | Topical |
| Background | Famotidine | Other / unclassified | 20 mg | — |
| Background | Ketorolac Tromethamine | Small molecule | 30 mg | — |
| Background | Lidocaine | Other / unclassified | — | Intrathecal |
| Background | Meloxicam | Small molecule | 7.5 mg | — |
| Background | Metoclopramide | Small molecule | 10 mg | — |
| Background | Midazolam | Small molecule | 2 mg | — |
| Background | Omeprazole | Other / unclassified | 20 mg | — |
| Background | Ondansetron | Other / unclassified | 4 mg | — |
| Background | Prednisone | Other / unclassified | 5 mg | — |
| Background | Pregabalin | Small molecule | 25 mg | — |
| Background | Pregabalin | Small molecule | 100 mg | — |
| Background | Propofol | Small molecule | 10 ug/kg | — |
| Background | Propofol | Small molecule | 125 ug/kg | — |
| Background | Tramadol | Other / unclassified | 50 mg | — |
| Background | Tranexamic Acid | Small molecule | 2 g | — |